Phospho-yap1
WebPhospho-YAP (Ser127) Antibody detects endogenous levels of YAP only when phosphorylated at serine 127. This antibody may cross-react with phospho-TAZ (Ser89). … WebMonoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP protein. Background YAP (Yes-associated protein, YAP65) was first identified based on its ability to associate with the SH3 domain of Yes.
Phospho-yap1
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WebMonoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser397 of human YAP protein isoform 1. … WebYAP1 encodes a nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis to play a pivotal role in controlling cell growth and organ size and has emerged as a key player in tumor suppression (2,3).
WebPhospho-YAP1 (Ser397) Antibody (PA5-110163) in WB Western blot analysis of Phospho-YAP1 (Ser397) in NIH/3T3, NIH/3T3 (treated with Forskolin). Samples were incubated in polyclonal Phospho-YAP1 (Ser397) antibody ( Product # PA5-110163) using a dilution of 1:1000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10000. Product Details WebAug 15, 2024 · Mechanistically, the post-mitotic state of the adult CM relies on ephrin-B1 sequestering of inactive phospho-Yap1, the effector of the Hippo-pathway, at the lateral membrane. Hence, ephrin-B1 repression leads to phospho-Yap1 release in the cytosol but CM quiescence at resting state. Upon cardiac stresses (apectomy, MI, senescence), Yap1 …
WebYAP1 Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein … WebAnti-phospho-YAP1 (pTyr357) antibody produced in rabbit has been used in western blotting [ 2] and immunofluorescence. Packaging 25, 100, 200 μL Biochem/physiol …
WebOct 2, 2024 · The Hippo pathway effector, Yes-associated protein (YAP), is a transcriptional coactivator implicated in cholangiocarcinoma (CCA) pathogenesis. YAP is known to be regulated by a serine/threonine kinase relay module (MST1/2–LATS1/2) culminating in phosphorylation of YAP at Serine 127 and cytoplasmic sequestration.
WebInvitrogen Anti-Phospho-YAP1 (Ser127) Polyclonal, Catalog # PA5-17481. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse, Rat samples. … simoniz wheel cleanerWebPhosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell … simoniz wheel silverWebFeb 27, 2024 · A phospho-resistant form of Yap1 was relocalized to the nucleus when Fat4 was downregulated , further supporting the conclusion that the nuclear translocation of Yap1 downstream of Fat4 is not ... simoniz wipes ratingsWebRecombinant Anti-YAP1 (phospho S127) antibody [EP1675Y] - BSA and Azide free (ab172374) Datasheet Submit a review Submit a question References (3) $905 Product size 100 µg $905 1 mg $8,985.00 Add to basket Order now and get it on Thursday March 02, 2024 Custom quote Bulk request Shipping info $50.00 to United States simoniz white primerWebJul 23, 2024 · The gene that has received the most attention in the literature is YAP1, which was found to be involved in the development and progression of CRC [ 5, 6, 9, 10 ]. The gene was reported to be overexpressed in 52.5% (73/139) of CRC, and the YAP1 protein was predominantly localized to the nucleus [ 11 ]. simoniz wheel brushWebAll lanes : Anti-YAP1 (phospho Y357) antibody [EPR23680-48] at 1/1000 dilution Lane 1 : HeLa (human cervix adenocarcinoma epithelial cell) whole cell lysate Lane 2 : HeLa whole cell lysate (phosphatase treated membrane) Lysates/proteins at 20 µg per lane. Secondary All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/20000 dilution ... simoniz wireless backup camera reviewWebIn line with this findings there was an increased level of non-phospho-(Active)YAP1(Ser127) and non-phospho-(Active)β-catenin(Ser33/37/Thr41) in the lung tissue (Fig. 3 B-C). In … simoniz wireless backup camera installation