Tsc1 antibody
WebApr 7, 2008 · Sensitivity and specificity of a rabbit monoclonal anti-TSC1 antibody was confirmed by staining of paraffin-embedded pellets of TSC1-null HCV29 cells and HCV29 in which wild-type TSC1 had been re-expressed (Fig. 7 A and D). Normal ureter showed strong cytoplasmic TSC1 expression in the urothelium (Fig. 7 E). WebAnti TSC1 pAb [Catalog No.: ATL-HPA074132] Toggle menu. Compare ; Phone: 760-431-4600 / Fax: 760-431-4604; Sign in or Register; Cart 0. Search. CURRENT PROMOTIONS. ... Primary Antibodies; Aicardi-Goutieres syndrome . All Aicardi-Goutieres syndrome; Labeled Proteins; Recombinant Antibodies; Alcohol Use Disorder . All Alcohol Use Disorder;
Tsc1 antibody
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WebFeb 4, 2024 · Tuberous sclerosis complex subunit 1 (TSC1) and 2 (TSC2) are frequently mutated in non–small cell lung cancer (NSCLC), however, their effects on antitumor immunity remained unexplored.A CRISPR screening in murine Kras G12D /Trp53 −/− (KP) model identified Tsc1 and Tsc2 as potent regulators of programmed cell death ligand 1 … WebNov 12, 2024 · TSC1/2-mutated PEComas sometimes respond to mTOR-inhibition therapy , but these drugs are mechanistically believed to be inefficient in TFE3-altered PEComa. MET-inhibitors, on the other hand, are active in alveolar soft part sarcoma with TFE3 rearrangement [ 20 ], a rare subtype of soft-tissue sarcoma, and could constitute a …
WebThis phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS312 of mouse TSC1. Storage. Aliquot the phospho-TSC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. WebLearn more about Anti-TSC1 Rabbit Polyclonal Antibody (PE (Phycoerythrin)). We enable science by offering product choice, services, process excellence and our people make it happen.
WebFeb 3, 2024 · Double labeling with Tsc1 (Hamartin) and H +-ATPase antibodies demonstrated remarkable colocalization in cyst epithelial cells in Tsc1 KO mice (Fig. 3B). Double labeling with Tsc1 and AQP-2 antibodies indicated the expression of Tsc1 in the majority of cells lining the cysts with few and distinct AQP-2–expressing (principal cells … WebAntibody was affinity purified using an epitope specific to TSC1 immobilized on solid support. The epitope recognized by A300-316A maps to a region between residue 1100 and the C-terminus (residue 1164) of human tuberous sclerosis 1 using the numbering given in Swiss-Prot entry Q92574 (GeneID 7248).
WebTuberous sclerosis complex (TSC) is an autosomal dominant disorder that is due to inactivating mutations in TSC1 (also known as hamartin) or TSC2 (also known as tuberin). TSC is featured by benign tumors (hamartomas ... (TSC1) (clone 1B2-2A8) antibody (upper). Proteins were visualized using a goat anti-mouse-IgG secondary antibody conjugated to ...
WebUrothelial carcinoma represents one of the most prevalent types of cancer worldwide, and its incidence is expected to grow. Although the treatment of the advanced disease was based on chemotherapy for decades, the developments of different therapies, such as immune checkpoint inhibitors, antibody drug conjugates and tyrosine kinase inhibitors, … higgins lumber ohioWebTSC1 Antibody, Biotin conjugated - Cat. #: CSB-PA849764LD01HU. Regular price $431.60 CAD Sale price $431.60 CAD Regular price how far is corsicana tx from conroe txWebMar 21, 2024 · In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, 28215400, 35772404).Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity … how far is corsicana texas from dallas texasWebNov 10, 2024 · Tsc1 was immunoprecipitated from HEK293 cell lysates using anti-Tsc1 antibody and immunoblotted with indicated antibodies to confirm chaperone, co-chaperone, and client protein interaction. IgG was used as control. FLAG-tagged Hsp90α N-, M-, and C-domains were transiently expressed and immunoprecipitated from HEK293 cells. how far is corsicana tx from athens txWebSep 1, 2010 · The TSC1 and TSC2 polyclonal antibodies used in this study were purchased from Santa Cruz Biotechnology and used at the manufacturer's recommended dilutions. The anti-T7Tag monoclonal antibody was from Novagen. … higgins lyme diseaseWebMedium consistency between antibody staining and RNA expression data. Medium consistency between antibody staining and RNA expression data. WESTERN BLOT i … how far is corsicana from houstonWebSep 18, 2024 · The TSC1 and TSC2 genes are connected to multiple syndromes from Tuberous Sclerosis ... The antitumor effects were linearly correlated with vaccinated mouse serum titers of GT198 antibody, ... how far is corsicana tx from tyler tx